Coloxyl with Senna

ADMINISTRATION ROUTES:

PO

ALTERNATIVE NAMES:

Coloxyl with Senna, Docusate sodium & Total Sennosides, Laxsol

ICU INDICATIONS:

1. Constipation

PRESENTATION AND ADMINISTRATION:

PO:

Coloxyl with Senna tablets (brown) - each contains 50 mg docusate / 8 mg sennoside

DOSAGE:

PO:

Two tablets BD

DOSAGE IN RENAL FAILURE AND RENAL REPLACEMENT THERAPY:

Dose as in normal renal function

DOSAGE IN PAEDIATRICS:

Not recommended in children, consider other agents

CLINICAL PHARMACOLOGY:

Faecal softener with peristaltic stimulant

CONTRAINDICATIONS:

1. Mechanical intestinal obstruction

WARNINGS:

See CONTRAINDICATIONS

PRECAUTIONS:

General:

Maintain adequate fluid intake

Laboratory Tests:

No tests in addition to standard ICU tests are required

Drug/Laboratory Test Interactions:

None known

IMPORTANT DRUG INTERACTIONS IN ICU:

None of note

ADVERSE REACTIONS:

Gastrointestinal System:

Cramps, diarrhoea, atonic colon (with chronic use)

Electrolytes:

Hypokalaemia